Conditional knockout of hypoxia-inducible factor 1-alpha in tumor-infiltrating neutrophils protects against pancreatic ductal adenocarcinoma

Conditional knockout of hypoxia-inducible factor 1-alpha in tumor-infiltrating neutrophils protects against pancreatic ductal adenocarcinoma

Large numbers of neutrophils infiltrate tumors and comprise a notable component of the inflammatory tumor microenvironment. While it is established that tumor cells exhibit the Warburg effect for energy production, the contribution of the neutrophil metabolic state to tumorigenesis is unknown. Here,...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Sieow, Je Lin, Leong, Penny Hweixian, Gun, Sin Yee, Tan, Ling Qiao, Duan, Kaibo, Yeong, Joe Poh Sheng, Pang, Angela, Lim, Diana, Toh, Han Chong, Lim, Tony Kiat Hon, Engleman, Edgar, Rotzschke, Olaf, Ng, Lai Guan, Chen, Jinmiao, Tan, Suet Mien, Wong, Siew Cheng
Awduron Eraill: School of Biological Sciences
Fformat: Journal Article
Iaith:English
Cyhoeddwyd: 2023
Pynciau:
Science::Biological sciences
Neutrophils
Pancreatic Cancer
Mynediad Ar-lein:https://hdl.handle.net/10356/169561

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https://hdl.handle.net/10356/169561

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