Conservation of red blood cell signalling in Plasmodium merozoite invasion
Red blood cells (RBC) possess essential signalling cascades that are involved in Plasmodium merozoite invasion. While P. falciparum reticulocyte binding protein homologue 5 (RH5) binding to RBC surface receptor Basigin is crucial for invasion and induces calcium (Ca2+) influx in the RBC, the mechani...
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Format: | Thesis-Doctor of Philosophy |
Language: | English |
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Nanyang Technological University
2023
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Online Access: | https://hdl.handle.net/10356/169702 |