The scaffold RhoGAP protein ARHGAP8/BPGAP1 synchronizes Rac and Rho signaling to facilitate cell migration

The scaffold RhoGAP protein ARHGAP8/BPGAP1 synchronizes Rac and Rho signaling to facilitate cell migration

Rho GTPases regulate cell morphogenesis and motility under the tight control of guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs). However, the underlying mechanism(s) that coordinate their spatiotemporal activities, whether separately or together, remain unclear. We s...

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Bibliographic Details
Main Authors: Wong, Darren Chen Pei, Pan, Catherine Qiurong, Er, Shi Yin, Thivakar, T., Tan, Rachel Zi Yi, Seah, Sock Hong, Chua, Pei Jou, Jiang, Tingting, Chew, Ti Weng, Chaudhuri, Parthiv Kant, Mukherjee, Somsubhro, Salim, Agus, Aye, Thike Aye, Koh, Cheng Gee, Lim, Chwee Teck, Tan, Puay Hoon, Bay, Boon Huat, Ridley, Anne J., Low, Boon Chuan
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2023
Subjects:
Science::Biological sciences
Rho Factor
Scaffold Protein
Online Access:https://hdl.handle.net/10356/169717

Internet

https://hdl.handle.net/10356/169717

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