Aβ-mediated nuclear pore complex dysfunction in a mouse model of alzheimer's disease
The nuclear pore complex (NPC) is a vital component of the nuclear envelope that regulates multiple processes including nucleocytoplasmic shuttling, chromosome organisation, and transcriptional regulation. While gradual loss of NPCs occurs in neurons during ageing, further dysregulation has been rep...
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| Format: | Thesis-Doctor of Philosophy |
| Language: | English |
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Nanyang Technological University
2023
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| Online Access: | https://hdl.handle.net/10356/169886 |