Polymeric STING pro-agonists for tumor-specific sonodynamic immunotherapy

The efficacy of combination immunotherapy has been limited by tumor specificity and immune-related adverse events (irAEs). Herein, we report the development of polymeric STING pro-agonists (PSPA), whose sono-immunotherapeutic efficacy is activated by sono-irradiation and elevated glutathione (GSH) w...

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Bibliographic Details
Main Authors: Yu, Jie, He, Shasha, Zhang, Chi, Xu, Cheng, Huang, Jingsheng, Xu, Mengke, Pu, Kanyi
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2023
Subjects:
Online Access:https://hdl.handle.net/10356/171012