Endocytosis of red blood cell extracellular vesicles by macrophages leads to cytoplasmic heme release and prevents foam cell formation in atherosclerosis

Extracellular vesicles (EVs) can be produced from red blood cells (RBCs) on a large scale and used to deliver therapeutic payloads efficiently. However, not much is known about the native biological properties of RBCEVs. Here, we demonstrate that RBCEVs are primarily taken up by macrophages and mono...

詳細記述

書誌詳細
主要な著者: Pham, Thach Tuan, Le, Anh Hong, Dang, Cong Phi, Chong, Suet Yen, Do, Dang Vinh, Peng, Boya, Jayasinghe, Migara Kavishka, Ong, Hong Boon, Hoang, Dong Van, Louise, Roma Anne, Loh, Yuin-Han, Hou, Han Wei, Wang, Jiong-Wei, Le, Minh T. N.
その他の著者: Lee Kong Chian School of Medicine (LKCMedicine)
フォーマット: Journal Article
言語:English
出版事項: 2023
主題:
オンライン・アクセス:https://hdl.handle.net/10356/171610