Endocytosis of red blood cell extracellular vesicles by macrophages leads to cytoplasmic heme release and prevents foam cell formation in atherosclerosis

Endocytosis of red blood cell extracellular vesicles by macrophages leads to cytoplasmic heme release and prevents foam cell formation in atherosclerosis

Extracellular vesicles (EVs) can be produced from red blood cells (RBCs) on a large scale and used to deliver therapeutic payloads efficiently. However, not much is known about the native biological properties of RBCEVs. Here, we demonstrate that RBCEVs are primarily taken up by macrophages and mono...

Full description

Bibliographic Details
Main Authors: Pham, Thach Tuan, Le, Anh Hong, Dang, Cong Phi, Chong, Suet Yen, Do, Dang Vinh, Peng, Boya, Jayasinghe, Migara Kavishka, Ong, Hong Boon, Hoang, Dong Van, Louise, Roma Anne, Loh, Yuin-Han, Hou, Han Wei, Wang, Jiong-Wei, Le, Minh T. N.
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2023
Subjects:
Science::Medicine
Atherosclerosis
Extracellular Vesicles
Online Access:https://hdl.handle.net/10356/171610

Internet

https://hdl.handle.net/10356/171610

Similar Items