Cytokine enrichment in deep cerebellar nuclei is contributed by multiple glial populations and linked to reduced amyloid plaque pathology

Cytokine enrichment in deep cerebellar nuclei is contributed by multiple glial populations and linked to reduced amyloid plaque pathology

Alzheimer's disease (AD) pathology and amyloid-beta (Aβ) plaque deposition progress slowly in the cerebellum compared to other brain regions, while the entorhinal cortex (EC) is one of the most vulnerable regions. Using a knock-in AD mouse model (App KI), we show that within the cerebellum, the...

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Bibliographic Details
Main Authors: Gaunt, Jessica Ruth, Zainolabidin, Norliyana, Yip, Alaric K. K., Tan, Jia Min, Low, Aloysius Y. T., Chen, Albert I., Ch'ng, Toh Hean
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2024
Subjects:
Science::Medicine
Alzheimer’s Disease
Microglia
Online Access:https://hdl.handle.net/10356/173055

Internet

https://hdl.handle.net/10356/173055

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