Assessing the permeability of supersaturating drug delivery system of amorphous drug-polyelectrolyte/protein nanoplexes in Caco-2 cell monolayer

Solubility enhancements of amorphous drug-polyelectrolyte and drug-protein nanoparticle complexes (nanoplexes) by virtue of their supersaturation generation were established previously. Their permeability across intestinal membrane, however, had not been assessed. The present work evaluated the memb...

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Bibliographic Details
Main Authors: Tran, The-Thien, Cheow, Wean Sin, Chua, Angeline, Yang, Guang, Poenar, Daniel Puiu, Hadinoto, Kunn
Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
Format: Journal Article
Language:English
Published: 2024
Subjects:
Online Access:https://hdl.handle.net/10356/173291