Cobalt's dual role in promoting C3-glycosylation of indoles: unraveling mechanistic insights

Cobalt's dual role in promoting C3-glycosylation of indoles: unraveling mechanistic insights

In this study, we present a cobalt-catalyzed C3-glycosylation of indoles using unfunctionalized glycals, yielding 3-indolyl-C-deoxyglycosides. These compounds hold promise as sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for treating type 2 diabetes. Control experiments unveiled that c...

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Bibliographic Details
Main Authors: Mu, Qiu-Qi, Guo, Aoxin, Cai, Xin, Qin, Yang-Yang, Liu, Xing-Le, Ye, Fang-Zhen, Yang, Hui-Jie, Xiao, Xiong, Liu, Xue-Wei
Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
Format: Journal Article
Language:English
Published: 2024
Subjects:
Chemistry
C3-Glycosylation
Indoles
Online Access:https://hdl.handle.net/10356/173474

Internet

https://hdl.handle.net/10356/173474

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