Allosteric inhibition of the T cell receptor by a designed membrane ligand

Allosteric inhibition of the T cell receptor by a designed membrane ligand

The T cell receptor (TCR) is a complex molecular machine that directs the activation of T cells, allowing the immune system to fight pathogens and cancer cells. Despite decades of investigation, the molecular mechanism of TCR activation is still controversial. One of the leading activation hypothese...

Full description

Bibliographic Details
Main Authors: Ye, Yujie, Morita, Shumpei, Chang, Justin J., Buckley, Patrick M., Wilhelm, Kiera B., DiMaio, Daniel, Groves, Jay T., Barrera, Francisco N.
Other Authors: Institute for Digital Molecular Analytics and Science (IDMxS)
Format: Journal Article
Language:English
Published: 2024
Subjects:
Chemistry
Ligands
Phosphorylation
Online Access:https://hdl.handle.net/10356/173766

Internet

https://hdl.handle.net/10356/173766

Similar Items