Allosteric inhibition of the T cell receptor by a designed membrane ligand
The T cell receptor (TCR) is a complex molecular machine that directs the activation of T cells, allowing the immune system to fight pathogens and cancer cells. Despite decades of investigation, the molecular mechanism of TCR activation is still controversial. One of the leading activation hypothese...
Main Authors: | , , , , , , , |
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Other Authors: | |
Format: | Journal Article |
Language: | English |
Published: |
2024
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/173766 |