Characterizing the interplay between super enhancers and chromatin interactions in cancer

Chromatin interactions are vital for regulating gene expression by connecting distal regulatory elements like enhancers and super enhancers (SEs) with target genes. Our study aims to uncover vulnerabilities in these complex networks and identify potential cancer treatment targets. We propose that SE...

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Bibliographic Details
Main Author: Choudhary, Ruchi
Other Authors: Melissa Jane Fullwood
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2024
Subjects:
Online Access:https://hdl.handle.net/10356/173896