Selective protein aggregation confines and inhibits endotoxins in wounds: linking host defense to amyloid formation

Selective protein aggregation confines and inhibits endotoxins in wounds: linking host defense to amyloid formation

Bacterial lipopolysaccharide (LPS) induces rapid protein aggregation in human wound fluid. We aimed to characterize these LPS-induced aggregates and their functional implications using a combination of mass spectrometry analyses, biochemical assays, biological imaging, cell experiments, and animal m...

Full description

Bibliographic Details
Main Authors: Petrlova, Jitka, Hartman, Erik, Petruk, Ganna, Lim, Jeremy Chun Hwee, Adav, Sunil Shankar, Kjellström, Sven, Puthia, Manoj, Schmidtchen, Artur
Other Authors: School of Materials Science and Engineering
Format: Journal Article
Language:English
Published: 2024
Subjects:
Engineering
Bacteriology
Immunology
Online Access:https://hdl.handle.net/10356/173914

Internet

https://hdl.handle.net/10356/173914

Similar Items