Elafibranor upregulates the EMT-inducer S100A4 via PPARβ/δ

Elafibranor upregulates the EMT-inducer S100A4 via PPARβ/δ

Elafibranor is a dual peroxisome proliferator-activated receptor (PPAR)α and β/δ agonist that has reached a phase III clinical trial for the treatment of metabolic dysfunction-associated steatotic liver disease (MASLD). Here, we examined the effects of elafibranor in mice fed a choline-deficient hig...

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Bibliographic Details
Main Authors: Zhang, Meijian, Barroso, Emma, Ruart, Maria, Peña, Lucía, Peyman, Mona, Aguilar-Recarte, David, Montori-Grau, Marta, Rada, Patricia, Cugat, Clara, Montironi, Carla, Zarei, Mohammad, Jurado-Aguilar, Javier, Camins, Antoni, Balsinde, Jesús, Valverde, Ángela M., Wahli, Walter, Palomer, Xavier, Vázquez-Carrera, Manuel
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2024
Subjects:
Medicine, Health and Life Sciences
Metabolic dysfunction-associated steatotic liver disease
Epithelial-mesenchymal transition
Online Access:https://hdl.handle.net/10356/174274

Internet

https://hdl.handle.net/10356/174274

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