Asymmetric synthesis of planar chiral carbonitriles and amines via carbene-catalyzed kinetic resolution

Asymmetric synthesis of planar chiral carbonitriles and amines via carbene-catalyzed kinetic resolution

We have developed a catalytic method using chiral N-heterocyclic carbene (NHC) as the sole organic catalyst to synthesize planar chiral carbonitriles asymmetrically, resulting in optically pure, multifunctional compounds. The method demonstrates remarkable tolerance toward diverse substituents and s...

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Bibliographic Details
Main Authors: Lv, Ya, Mou, Chengli, Liu, Qian, Shu, Liangzhen, Cai, Yuanlin, Lv, Xiaokang, Jin, Zhichao, Chi, Robin Yonggui
Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
Format: Journal Article
Language:English
Published: 2024
Subjects:
Chemistry
Amine
Carbene
Online Access:https://hdl.handle.net/10356/174360

Internet

https://hdl.handle.net/10356/174360

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