Aberrant non-canonical NF-κB signalling reprograms the epigenome landscape to drive oncogenic transcriptomes in multiple myeloma

In multiple myeloma, abnormal plasma cells establish oncogenic niches within the bone marrow by engaging the NF-κB pathway to nurture their survival while they accumulate pro-proliferative mutations. Under these conditions, many cases eventually develop genetic abnormalities endowing them with const...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak: Ang, Daniel Aron, Carter, Jean-Michel, Deka, Kamalakshi, Tan, Joel H. L., Zhou, Jianbiao, Chen, Qingfeng, Chng, Wee Joo, Harmston, Nathan, Li, Yinghui
Beste egile batzuk: School of Biological Sciences
Formatua: Journal Article
Hizkuntza:English
Argitaratua: 2024
Gaiak:
Sarrera elektronikoa:https://hdl.handle.net/10356/174697