Interaction of SIRT6 with telomeric chromatin in the context of ageing and cancer
Sirtuin 6 (SIRT6) is a NAD+-dependent deacetylase with known functions in maintaining telomere integrity and cellular homeostasis. Early reports revealed the role of SIRT6 as a histone deacetylase while increasing studies have shown the protein’s involvement in regulating chromatin organisation. Whi...
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| Format: | Final Year Project (FYP) |
| Language: | English |
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Nanyang Technological University
2024
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| Online Access: | https://hdl.handle.net/10356/175445 |