Interaction of SIRT6 with telomeric chromatin in the context of ageing and cancer

Sirtuin 6 (SIRT6) is a NAD+-dependent deacetylase with known functions in maintaining telomere integrity and cellular homeostasis. Early reports revealed the role of SIRT6 as a histone deacetylase while increasing studies have shown the protein’s involvement in regulating chromatin organisation. Whi...

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Bibliographic Details
Main Author: Teh, Zhi Jing
Other Authors: Lars Nordenskiöld
Format: Final Year Project (FYP)
Language:English
Published: Nanyang Technological University 2024
Subjects:
Online Access:https://hdl.handle.net/10356/175445