Epigenetic landscapes of De Novo Serine synthesis pathway in natural killer/T cell lymphoma (NKTL)

During cancer growth and metastasis, large demand of biomass often results in cancer cells encountering lack of nutrients. The lack of extracellular amino acids can lead to the induction of the integrated stress response (ISR). The ISR is mediated by phosphorylated eIF2-alpha (eIF2α) and activating...

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Bibliographic Details
Main Author: Zhang, Jiexin
Other Authors: -
Format: Final Year Project (FYP)
Language:English
Published: Nanyang Technological University 2024
Subjects:
Online Access:https://hdl.handle.net/10356/176175