Purine and carbohydrate availability drive Enterococcus faecalis fitness during wound and urinary tract infections

Purine and carbohydrate availability drive Enterococcus faecalis fitness during wound and urinary tract infections

Although E. faecalis is a common wound pathogen, its pathogenic mechanisms during wound infection are unexplored. Here, combining a mouse wound infection model with in vivo transposon and RNA sequencing approaches, we identified the E. faecalis purine biosynthetic pathway and galactose/mannose MptAB...

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Bibliographic Details
Main Authors: Tan, Casandra Ai Zhu, Chong, Kelvin Kian Long, Yeong, Daryl Yu Xuan, Ng, Celine Hui Min, Muhammad Hafiz Ismail, Yap, Zhei Hwee, Khetrapal, Varnica, Tay, Vanessa Shi Yun, Drautz-Moses, Daniela I., Ali, Yusuf, Chen, Swaine L., Kline, Kimberly A.
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2024
Subjects:
Medicine, Health and Life Sciences
Carbohydrates
Fitness determinants
Online Access:https://hdl.handle.net/10356/178572

Internet

https://hdl.handle.net/10356/178572

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