Dichotomous transactivation domains contribute to growth inhibitory and promotion functions of TAp73

The transcription factor p73, a member of the p53 tumor-suppressor family, regulates cell death and also supports tumorigenesis, although the mechanistic basis for the dichotomous functions is poorly understood. We report here the identification of an alternate transactivation domain (TAD) located a...

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Bibliographic Details
Main Authors: Li, Dan, Kok, Catherine Yen Li, Wang, Chao, Ray, Debleena, Osterburg, Susanne, Dötsch, Volker, Ghosh, Sujoy, Sabapathy, Kanaga
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2024
Subjects:
Online Access:https://hdl.handle.net/10356/178972