Chaperone-assisted multiphase condensation of RNA-binding-deficient TDP-43

From previous report, RNA-binding-deficient TDP-43 undergoes multiphasic condensation through liquid-liquid phase separation (LLPS), with Hsp70 chaperones enriched in the core of these structures. In addition to Hsp70, my thesis introduces the novel finding of Hsp40 co-chaperones also being enriched...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखक: Yeo, Kian Hua
अन्य लेखक: Choe Young Jun
स्वरूप: Thesis-Doctor of Philosophy
भाषा:English
प्रकाशित: Nanyang Technological University 2024
विषय:
ऑनलाइन पहुंच:https://hdl.handle.net/10356/179292