Chaperone-assisted multiphase condensation of RNA-binding-deficient TDP-43
From previous report, RNA-binding-deficient TDP-43 undergoes multiphasic condensation through liquid-liquid phase separation (LLPS), with Hsp70 chaperones enriched in the core of these structures. In addition to Hsp70, my thesis introduces the novel finding of Hsp40 co-chaperones also being enriched...
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| Format: | Thesis-Doctor of Philosophy |
| Language: | English |
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Nanyang Technological University
2024
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| Online Access: | https://hdl.handle.net/10356/179292 |