Catalytic N-acylation for access to N-N atropisomeric N-aminoindoles: choice of acylation reagents and mechanistic insights
The synthesis of N-N axial compounds containing aromatic acyl amides using common acylation reagents remains challenging. We describe a highly atropenantioselective synthesis of N-aminoindoles containing N-N axes. A chiral cyclic isothiourea is used as the sole organic catalyst in the atropenantiose...
| Principais autores: | , , , , , |
|---|---|
| Outros Autores: | |
| Formato: | Journal Article |
| Idioma: | English |
| Publicado em: |
2024
|
| Assuntos: | |
| Acesso em linha: | https://hdl.handle.net/10356/179389 |