Demuxafy: improvement in droplet assignment by integrating multiple single-cell demultiplexing and doublet detection methods

Demuxafy: improvement in droplet assignment by integrating multiple single-cell demultiplexing and doublet detection methods

Recent innovations in single-cell RNA-sequencing (scRNA-seq) provide the technology to investigate biological questions at cellular resolution. Pooling cells from multiple individuals has become a common strategy, and droplets can subsequently be assigned to a specific individual by leveraging their...

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Bibliographic Details
Main Authors: Neavin, Drew, Senabouth, Anne, Arora, Himanshi, Lee, Jimmy Tsz Hang, Ripoll-Cladellas, Aida, Franke, Lude, Prabhakar, Shyam, Ye, Jimmie Chun, McCarthy, Davis J., Melé, Marta, Hemberg, Martin, Powell, Joseph E.
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2024
Subjects:
Medicine, Health and Life Sciences
Single-cell analysis
Genetic demultiplexing
Online Access:https://hdl.handle.net/10356/179610

Internet

https://hdl.handle.net/10356/179610

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