Disentangling oncogenic amplicons in esophageal adenocarcinoma

Disentangling oncogenic amplicons in esophageal adenocarcinoma

Esophageal adenocarcinoma is a prominent example of cancer characterized by frequent amplifications in oncogenes. However, the mechanisms leading to amplicons that involve breakage-fusion-bridge cycles and extrachromosomal DNA are poorly understood. Here, we use 710 esophageal adenocarcinoma cases w...

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Manylion Llyfryddiaeth
Prif Awduron: Ng, Alvin Wei Tian, McClurg, Dylan Peter, Wesley, Ben, Zamani, Shahriar A., Black, Emily, Miremadi, Ahmad, Giger, Olivier, Hoopen, Rogier Ten, Devonshire, Ginny, Redmond, Aisling M., Grehan, Nicola, Jammula, Sriganesh, Blasko, Adrienn, Li, Xiaodun, Aparicio, Samuel, Tavaré, Simon, Nowicki-Osuch, Karol, Fitzgerald, Rebecca C.
Awduron Eraill: Lee Kong Chian School of Medicine (LKCMedicine)
Fformat: Journal Article
Iaith:English
Cyhoeddwyd: 2024
Pynciau:
Medicine, Health and Life Sciences
Adenocarcinoma
Clonal evolution
Mynediad Ar-lein:https://hdl.handle.net/10356/179745

Rhyngrwyd

https://hdl.handle.net/10356/179745

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