Design and characterization of a new formulation for the delivery of COVID-19-mRNA vaccine to the nasal mucosa

Chitosan, a natural polysaccharide derived from chitin, possesses biocompatibility, biodegradability, and mucoadhesive characteristics, making it an attractive material for the delivery of mRNA payloads to the nasal mucosa and promoting their uptake by target cells such as epithelial and immune cell...

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Bibliographic Details
Main Authors: Benetti, Ayça Altay, Tan, Eugene Yang Zhi, Chang, Zi Wei, Bae, Ki Hyun, Thwin, Ma Thinzar, Muthuramalingam, Ram Pravin Kumar, Liao, Kuo-Chieh, Wan, Yue, Ng, Lisa F. P., Renia, Laurent, Liu, Jianping, Chen, Xiaoyuan, Yang, Yi Yan, White, Kevin P., Pastorin, Giorgia
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2024
Subjects:
Online Access:https://hdl.handle.net/10356/179841