Structural investigations on the mitochondrial uncouplers niclosamide and FCCP

There has been renewed interest in using mitochondrial uncoupler compounds such as niclosamide and carbonyl cyanide p-(trifluoromethoxy)phenylhydrazone (FCCP) for the treatment of obesity, hepatosteatosis and diseases where oxidative stress plays a role. However, both FCCP and niclosamide have undes...

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Autors principals: Ng, Mei Ying, Song, Zhi Jian, Tan, Choon Hong, Bassetto, Marcella, Hagen, Thilo
Altres autors: School of Physical and Mathematical Sciences
Format: Journal Article
Idioma:English
Publicat: 2024
Matèries:
Accés en línia:https://hdl.handle.net/10356/179914