Using organoid xenograft model of PKD to validate novel pathological pathways revealed by single cell analysis

PKD is a major global health concern, contributing significantly to end-stage renal disease. Current therapeutic challenges in PKD stem from its complex pathogenesis, requiring extensive research to identify effective targets and unravel signaling networks. While notable advances have been made usin...

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Bibliographic Details
Main Author: Zhang, Tian
Other Authors: Xia Yun
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2024
Subjects:
Online Access:https://hdl.handle.net/10356/180024