Bosutinib stimulates macrophage survival, phagocytosis, and intracellular killing of bacteria

Bosutinib stimulates macrophage survival, phagocytosis, and intracellular killing of bacteria

Host-acting compounds are emerging as potential alternatives to combating antibiotic resistance. Here, we show that bosutinib, an FDA-approved chemotherapeutic for treating chronic myelogenous leukemia, does not possess any antibiotic activity but enhances macrophage responses to bacterial infection...

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Bibliographic Details
Main Authors: da Silva, Ronni A. G., Stocks, Claudia J., Hu, Guangan, Kline, Kimberly A., Chen, Jianzhu
Other Authors: Singapore-MIT Alliance for Research and Technology Centre
Format: Journal Article
Language:English
Published: 2024
Subjects:
Medicine, Health and Life Sciences
Immunomodulation
Wound infection
Online Access:https://hdl.handle.net/10356/180061

Internet

https://hdl.handle.net/10356/180061

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