Bosutinib stimulates macrophage survival, phagocytosis, and intracellular killing of bacteria
Host-acting compounds are emerging as potential alternatives to combating antibiotic resistance. Here, we show that bosutinib, an FDA-approved chemotherapeutic for treating chronic myelogenous leukemia, does not possess any antibiotic activity but enhances macrophage responses to bacterial infection...
Main Authors: | da Silva, Ronni A. G., Stocks, Claudia J., Hu, Guangan, Kline, Kimberly A., Chen, Jianzhu |
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Other Authors: | Singapore-MIT Alliance for Research and Technology Centre |
Format: | Journal Article |
Language: | English |
Published: |
2024
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/180061 |
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