Cellular uptake of phase-separating peptide coacervates

Peptide coacervates self-assembling via liquid-liquid phase separation are appealing intracellular delivery vehicles of macromolecular therapeutics (proteins, DNA, mRNA) owing to their non-cytotoxicity, high encapsulation capacity, and efficient cellular uptake. However, the mechanisms by which thes...

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Bibliographic Details
Main Authors: Shebanova, Anastasia, Perrin, Quentin Moana, Zhu, Kexin, Gudlur, Sushanth, Chen, Zilin, Sun, Yue, Huang, Congxi, Lim, Zhi Wei, Mondarte, Evan Angelo, Sun, Ruoxuan, Lim, Sierin, Yu, Jing, Miao, Yansong, Parikh, Atul N., Ludwig, Alexander, Miserez, Ali
Other Authors: School of Materials Science and Engineering
Format: Journal Article
Language:English
Published: 2024
Subjects:
Online Access:https://hdl.handle.net/10356/180615