Saccharide-assisted resolution of bioactive chiral carboxylic acids via NHC-catalyzed regioselective transesterification

The utility of unprotected saccharides as chiral auxiliaries in asymmetric synthesis remains largely undeveloped despite their ready availability, configurational diversity, and chiral purity. Here, we disclose an efficient achiral NHC catalytic strategy to regioselectively install racemic α,α-disub...

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Bibliographic Details
Main Authors: Dai, Shuolu, Zou, Juan, Wang, Haiqi, Xu, Min, Xu, Erjuan, Song, Jia, Hong, Yu, Li, Shaojun, Lv, Wen-Xin, Chi, Robin Yonggui
Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
Format: Journal Article
Language:English
Published: 2024
Subjects:
Online Access:https://hdl.handle.net/10356/180831