Sustained antibiotic release from biodegradable gelatin–silica hybrid for orthopedic infections

Sustained antibiotic release from biodegradable gelatin–silica hybrid for orthopedic infections

Antibiotic-loaded polymethylmethacrylate (PMMA) beads are commonly employed to treat prosthetic joint infections (PJI) and chronic osteomyelitis due to their excellent mechanical strength. However, PMMA's non-degradability results in a burst release of antibiotics and potential renal toxicity,...

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Bibliographic Details
Main Authors: Lin, Yu-Chien, Lee, Chin-Yun, Jones, Julian R., Liu, Wai-Ching, Cho, Nam-Joon, Hu, Chih-Chien, Chung, Ren-Jei
Other Authors: School of Materials Science and Engineering
Format: Journal Article
Language:English
Published: 2024
Subjects:
Engineering
Antibacterial activity
Biodegradable
Online Access:https://hdl.handle.net/10356/181065

Internet

https://hdl.handle.net/10356/181065

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