Development of physiological-based pharmacokinetic model 1 - model synthesis

This project aims to improve on an existing physiological-based pharmacokinetic (PBPK) model on rats for drug candidate diazepam. The existing PBPK model has large discrepancy with the experimental results especially on the hepatic and gut tissue drug concentration. The existing PBPK discuss on intr...

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Bibliographic Details
Main Author: Tan, Lisa Ying Xiu.
Other Authors: Koh Tong San
Format: Final Year Project (FYP)
Language:English
Published: 2009
Subjects:
Online Access:http://hdl.handle.net/10356/18196