A nitroreductase-activatable metabolic reporter for covalent labeling of pathological hypoxic cells in tumorigenesis

Aberrant hypoxic stress will initiate a cascade of pathological consequence observed prominently in tumorigenesis. Understanding of hypoxia's role in tumorigenesis is highly essential for developing effective therapeutics, which necessitates reliable tools to specifically distinguish hypoxic tu...

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التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Wang, Zhimin, Lau, Jun Wei, Liu, Songhan, Ren, Ziheng, Gong, Zhiyuan, Liu, Xiaogang, Xing, Bengang
مؤلفون آخرون: School of Chemistry, Chemical Engineering and Biotechnology
التنسيق: Journal Article
اللغة:English
منشور في: 2025
الموضوعات:
الوصول للمادة أونلاين:https://hdl.handle.net/10356/182206