Cell biology and mechanistic basis of elevated netosis in diabetes

When activated, neutrophils can unravel their chromatin and release it along with toxic granular proteins, forming neutrophil extracellular traps (NETs). Being highly pro-inflammatory, NETs are injurious to organs and tissues. In diabetes, formation of NETs (NETosis) is exacerbated, causing diabetic...

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Bibliographic Details
Main Author: Wang, Liang De
Other Authors: Christine Wong Siu Ling
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2025
Subjects:
Online Access:https://hdl.handle.net/10356/182659