Cell biology and mechanistic basis of elevated netosis in diabetes
When activated, neutrophils can unravel their chromatin and release it along with toxic granular proteins, forming neutrophil extracellular traps (NETs). Being highly pro-inflammatory, NETs are injurious to organs and tissues. In diabetes, formation of NETs (NETosis) is exacerbated, causing diabetic...
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Format: | Thesis-Doctor of Philosophy |
Language: | English |
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Nanyang Technological University
2025
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Online Access: | https://hdl.handle.net/10356/182659 |