A computational approach for drug repurposing towards Huntington's disease
Huntington’s Disease (HD) is an incurable neurodegenerative disease caused by the CAG expansion in the Huntingtin gene. Although its genetic cause is well-defined, the mechanism leading to HD pathology is poorly understood. This work hypothesises that in silico drug repurposing (ISDR) through transc...
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| Format: | Thesis-Doctor of Philosophy |
| Language: | English |
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Nanyang Technological University
2025
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| Online Access: | https://hdl.handle.net/10356/182739 |