Ni-MOF engineered system targeting macrophage aurora A kinase for bone loss prevention through PD-L1 activation

Ni-MOF engineered system targeting macrophage aurora A kinase for bone loss prevention through PD-L1 activation

Postmenopausal bone loss due to estrogen deficiency necessitates effective therapeutic strategies. Our study explores targeting macrophage Aurora A kinase to mitigate bone loss. Aurora A kinase phosphorylation is observed being increased in bone marrow-derived macrophages (BMDMs) from ovariectomy (O...

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Bibliographic Details
Main Authors: Zhang, Wenqian, Zhang, Shengming, He, Minghao, Hu, Weixian, Han, Wenhao, Zha, Kangkang, Feng, Qian, Liu, Guohui, Zhao, Yanli, Mi, Bobin
Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
Format: Journal Article
Language:English
Published: 2025
Subjects:
Medicine, Health and Life Sciences
Angiogenesis
Aurora A kinase
Online Access:https://hdl.handle.net/10356/182775

Internet

https://hdl.handle.net/10356/182775

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