Bufalin CaCO3 nanoparticles triggered pyroptosis through calcium overload via Na+/Ca2+ exchanger reverse for cancer immunotherapy

Bufalin CaCO3 nanoparticles triggered pyroptosis through calcium overload via Na+/Ca2+ exchanger reverse for cancer immunotherapy

Bufalin is a promising active ingredient in traditional Chinese medicine but has shown limited anticancer applications due to its toxicity. Here, we report BCNPs@gel, a bufalin-containing CaCO3 nanoparticle hydrogel, for enhancing cancer treatment through inducing cellular pyroptosis. Under the tumo...

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Bibliographic Details
Main Authors: Li, Tingxuan, Zhang, Yitong, Li, Hanyue, Zhang, Hanjie, Xie, Juntao, Li, Zimu, Zhang, Kai, Yu, Yongkang, Mei, Lin
Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
Format: Journal Article
Language:English
Published: 2025
Subjects:
Medicine, Health and Life Sciences
Pyroptosis
Bufalin
Online Access:https://hdl.handle.net/10356/182783

Internet

https://hdl.handle.net/10356/182783

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