Functional and structural studies of the flavivirus RNA-dependent RNA polymerase

Dengue fever, a neglected emerging disease for which no vaccine or antiviral agents exist at present, is caused by dengue virus, a member of the Flavivirus genus. The NS5 protein from dengue virus (DENV) is bi-functional and contains 900 amino acids. The S-adenosyl methionine transferase activity re...

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Bibliographic Details
Main Author: Yap, Thai Leong
Other Authors: Subhash Vasudevan
Format: Thesis
Language:English
Published: 2009
Subjects:
Online Access:https://hdl.handle.net/10356/18856