Detection of variant of hepatitis B virus and beta-globin through DNA technology

Two systems, i) the HBV precore gene, and ii) the human 0-globin gene were used as models to develop simple, reliable and fast methods for the detection of point mutations. Three PCR-based methods were employed to detect the HBV precore stop codon mutant. They are RG-PCR, SSCP analysis and non-radio...

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Bibliographic Details
Main Author: Chia, Chee Poh.
Other Authors: Gan Yap, Yik Yuen
Format: Thesis
Language:English
Published: 2009
Subjects:
Online Access:http://hdl.handle.net/10356/20362