Functional characterization of coronavirus non-structural proteins
Genetic manipulation of the RNA genomes by reverse genetics is a powerful tool to study the molecular biology and pathogenesis of RNA viruses. During construction of an infectious clone from a Vero cell-adapted coronavirus infectious bronchitis virus (IBV), we found that a G - C point mutation at nu...
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Format: | Thesis |
Language: | English |
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2010
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Online Access: | https://hdl.handle.net/10356/39373 |