N-heterocyclic carbene-catalyzed intramolecular stetter reaction between an aldehyde and activated alkyne for easy access to chromones.
A mild and efficient method for an intramolecular carbon-carbon bond formation between sp2 carbon (aldehyde) and sp carbon (activated alkyne) has been developed using N-Heterocyclic carbene catalyst. This method allows the usage of salicylaldehyde derivatives to assemble a wide pool of chromone deri...
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Format: | Final Year Project (FYP) |
Language: | English |
Published: |
2010
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Online Access: | http://hdl.handle.net/10356/39818 |