Synthetic route to quinolines via microwave irradiation assisted triflic acid-catalyzed friedländer annulation.
An efficient triflic acid-catalyzed Friedländer annulation of 2-aminobenzophenone and ketone to afford quinolines under microwave irradiation is reported herein. The methodology gives a variety of quinolines with moderate to high yields (30-90%), achieved with 5 mol% of the Brønsted acid.
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Format: | Final Year Project (FYP) |
Sprog: | English |
Udgivet: |
2010
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Online adgang: | http://hdl.handle.net/10356/39834 |