Epigenetic analysis of hepatocellular carcinoma development : involvement of HBV-modulated DNA methylation

Hepatocellular carcinoma (HCC) is one of the most aggressive human malignancies. Epidemiological studies have shown that HCC is closely associated with chronic hepatitis B virus (HBV). However, the underlying mechanisms of the HBV-associated HCC development remain unclear. DNA methylation, one of th...

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Bibliographic Details
Main Author: Niu, Dandan
Other Authors: Chen Wei Ning, William
Format: Thesis
Language:English
Published: 2010
Subjects:
Online Access:https://hdl.handle.net/10356/40634