Modulation of sphingolipids, cholesterol and saturated fatty acids interact with the neurodegeneration in the Drosophila blue cheese mutant.

The accumulation of insoluble ubiquitinated protein aggregates characterizes many neurodegenerative diseases such as Alzheimer’s disease. Some of these diseases are associated with perturbation of sphingolipids and cholesterol homeostasis. To elucidate the association between aberrant metabolism of...

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Bibliographic Details
Main Author: Boo, George.
Other Authors: School of Biological Sciences
Format: Final Year Project (FYP)
Language:English
Published: 2011
Subjects:
Online Access:http://hdl.handle.net/10356/42793