Study of islet amyloid polypeptide aggregation and its inhibition mechanisms.
Islet amyloid polypeptide (IAPP), a 37-amino acid polypeptide hormone of calcitonin family, is co-expressed and co-secreted with insulin in pancreatic islet β cells. Abnormal aggregation of islet amyloid polypeptide (IAPP) into amyloid fibrils is a hallmark of type 2 diabetes. Determining the molec...
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| Format: | Thesis |
| Language: | English |
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2011
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| Online Access: | http://hdl.handle.net/10356/42907 |