Rac inactivation decreases cell adhesion strength in chronic myeloid leukaemia
Chronic myeloid leukemia is a hematological malignancy characterized by the reciprocal translocation between chromosomes 9 and 22, resulting in the expression of the constitutively active tyrosine kinase BCR-ABL. The treatment of chronic myeloid leukemia by the tyrosine kinase inhibitior, imatinib,...
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Final Year Project (FYP) |
| Language: | English |
| Published: |
2011
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/10356/45681 |