Elucidating the role of prolidase in impairment of insulin signaling via abnormalities in integrinβ1 signaling pathway.
In this research project, novel gene PEPD encoding for prolidase enzyme was found to be linked to Type 2 Diabetes Mellitus. We investigated the 1) differences in PEPD mRNA and protein expression in insulin-sensitive versus insulin-resistant muscle samples; and if 2) associated prolidase, in...
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Format: | Final Year Project (FYP) |
Language: | English |
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2011
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Online Access: | http://hdl.handle.net/10356/46187 |