Linker prediction in fragment-based drug design.
Fragment-based drug design is a drug discovery technique where 2 fragments each having some degree of pharmacological activity is covalently tethered together using a linker to reap the energetic benefit of their combined pharmacological action. However, the effects of the linker on the binding ener...
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| Format: | Final Year Project (FYP) |
| Language: | English |
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2011
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| Online Access: | http://hdl.handle.net/10356/46708 |